| Date | Location | Result | |
| 3/2/12 | Asheville, N.C. (Kimmel Arena) | Wofford 64, College of Charleston 53 | Box score |
| 02/25/12 | Greenville, S.C. (Timmons Arena) | College of Charleston 68, Furman 61 | Box score |
| 02/20/12 | Charleston, SC (TD Arena) | Elon 63, College of Charleston 50 | Box score |
| 02/18/12 | Charleston, S.C. (TD Arena) | UNCG 60, College of Charleston 54 | Box score |
| 02/13/12 | Birmingham, Ala. (Pete Hanna Center) | Samford 70, College of Charleston 56 | Box score |
| 02/11/12 | Chattanooga, Tenn. (The McKenzie Arena) | Chattanooga 57, College of Charleston 31 | Box score |
| 02/06/12 | Charleston, S.C. (TD Arena) | Appalachian State 50, College of Charleston 41 | Box score |
| 02/04/12 | Charleston, S.C. (TD Arena) | Davidson 46, College of Charleston 23 | Box score |
| 02/01/12 | Cullowhee, N.C. (Ramsey Center) | Western Carolina 59, College of Charleston 45 | Box score |
| 1/28/12 | Statesboro, Ga. (Hanner Fieldhouse) | College of Charleston 47, Georgia Southern 44 | Box score |
| 01/23/12 | Charleston, S.C. (TD Arena) | College of Charleston 54, Western Carolina 39 | Box score |
| 1/21/12 | Spartanburg, S.C. (Benjamin Johnson) | College of Charleston 56, Wofford 55 | Box score |
| 01/18/12 | Charleston, S.C. (TD Arena) | Georgia Southern 35, College of Charleston 34 | Box score |
| 1/15/12 | Elon, N.C. (Alumni Gym) | Elon 51, College of Charleston 46 | Box score |
| 01/13/12 | Greensboro, N.C. | College of Charleston 52, UNCG 42 | Box score |
| 01/09/12 | Charleston, SC (TD Arena) | Samford 60, College of Charleston 54 | Box score |
| 01/07/12 | Charleston, S.C. (TD Arena) | Chattanooga 58, College of Charleston 44 | Box score |
| 01/02/12 | Charleston, S.C. (TD Arena) | Wingate 69, College of Charleston 60 | Box score |
| 12/29/11 | New Orleans, La. (Fogelman Arena) | Central Michigan 72, College of Charleston 69 | Box score |
| 12/28/11 | New Orleans, La. (Fogelman Arena) | Tulane 57, College of Charleston 42 | Box score |
| 12/21/11 | TD Arena, Charleston, S.C. | Connecticut 72, College of Charleston 24 | Box score |
| 12/19/11 | Boone, N.C. (Holmes Center) | Appalachian State 71, College of Charleston 52 | Box score |
| 12/17/11 | Davidson, N.C. - John M. Belk Arena | Davidson 56, College of Charleston 39 | Box score |
| 12/05/11 | Charleston, S.C. (TD Arena) | College of Charleston 49, Wofford 44 | Box score |
| 12/03/11 | Charleston, S.C. (TD Arena) | Furman 60, College of Charleston 51 | Box score |
| 11/30/11 | Charleston, S.C. (TD Arena) | Charleston Southern 64, College of Charleston 45 | Box score |
| 11/23/11 | Columbia, S.C./Colonial Life Arena | South Carolina 59, College of Charleston 40 | Box score |
| 11/17/11 | Stegeman Coliseum -- Athens, Ga. | Georgia 73, College of Charleston 48 | Box score |
| 11/14/11 | Conway, S.C. - Kimbel Arena | Coastal Carolina 59, College of Charleston 36 | Box score |
| 11/11/11 | Charleston, S.C. | College of Charleston 58, East Carolina 43 | Box score |